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KMID : 0895820030130010023
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Journal of Oriental Rehabilitation Medicine
2003 Volume.13 No. 1 p.23 ~ p.35
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Histomorphologic Effect of Carthami Semen Extract On Osteoporosis In Ovariectomized Rats
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Park Seok-Woo
Park Young-Hoi
Keum Dong-Ho
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Abstract
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Object: This study was carried out to investigate histomorphologic effect of Carthami Semen Extract On Osteoporosis In Ovariectomized Rats.
Methods: We used 15 female Sprague-Dawley rats. They were divided three groups, control and sham operated, Carthami Semen. We stained the specimens with Goldner,s modified Masson,s Trichrome. And then we measured bone histomorphometry using bioquant computer program of image-analysis system.
The measurements included static parameter and dynamic parameter. We measured the thickness of osteoid and callus, and bone volume as static parameter, and mineral apposition rate as dynamic parameter.
Results and Conclusions:
1. In the change of Ca, P there was no significant change between Carthami Semen and control group.
2. The Osteoid thickness and bone volume was increased in Carthami Semen group compared with control group.
3. The Cortical thickness and MAR was not significantly changed in Carthami Semen group compared with control group.
From above result, it appears that Carthami Semen have effective on osteoporosis.
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KEYWORD
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Carthami Semen, Osteoporosis
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